Dr. Navneet Sharma | Dr. Mallika Pathak | Category: Pharmaceutical Chemistry | Pharmaceutical Technology | Physical Pharmacy | Biopharmaceutics and Pharmacokinetics | Regulatory Affairs and Quality Assurance
Binding Type: Paperback Binding
Book Details
ISBN: 9789392062384
YOP: 2025
Pages: 654
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About the Book
This comprehensive volume explores the multifaceted realm of drug delivery systems, offering an in-depth examination of both foundational principles and emerging innovations in the field. Structured into three major thematic sections, the book begins by delving into drug delivery technologies, establishing the theoretical and molecular underpinnings of targeted drug delivery. Readers are guided through the mechanisms of drug release, uptake phenomena, and encapsulation strategies, with particular emphasis on the role of nanomaterials and the key factors influencing their performance.
The second section focuses on the efficiency, metabolism, and excretion of drug delivery carriers. It presents an extensive overview of novel systems such as liposomes, resealed erythrocytes, nanoparticles, dendrimers, and emulsions. Each chapter provides detailed insights into the structural and functional characteristics of these carriers, discussing their design, biological interactions, and potential to enhance therapeutic efficacy.
The final section addresses the chemical, pharmaceutical, and clinical aspects of drug technology development. It navigates through essential stages of drug development, from lead identification and optimization to the progression of investigational new drugs, clinical trial phases, and pilot-scale manufacturing. This part effectively bridges the gap between laboratory innovation and clinical application, highlighting current advancements and regulatory frameworks critical to the successful commercialization of new therapies.
Designed for students, researchers, and professionals in pharmaceutical sciences, this book serves both as a rigorous academic reference and a practical guide. Its interdisciplinary approach, enriched by expert contributions, positions it as an essential resource in the evolving landscape of drug delivery and biomedical research.
About the Editors
Dr. Navneet Sharma is a renowned scientist in pharmaceutical chemistry, biomaterials, and contamination sciences. He holds an M. Pharm from JSS University, a Postgraduate Diploma in Drug Regulatory Affairs from Jamia Hamdard, and a Ph.D. in Pharmaceutical Sciences from the University of Delhi. His doctoral work at INMAS (DRDO) focused on developing topical formulations for chemical, biological, radiological, and nuclear (CBRN) skin decontamination, incorporating toxicological assessments and cellular studies.
Dr. Sharma’s postdoctoral research at IIT Delhi led to the development of zinc titanate-based biodegradable materials for CBRN decontamination, integrating nanomaterials for improved efficacy and sustainability. He also spearheaded a DST-funded COVID-19 project that produced antiviral coatings effective against SARS-CoV-2 and H1N1, leading to two patents and successful technology transfer. His innovations earned him the SCO Best Innovation Award (2020) and DST Young Scientist Awards (2018, 2022).
With over fifty publications, five edited books, and ten patents—five of which have been licensed—Dr. Sharma’s contributions to biomaterial-based drug delivery and wound healing continue to impact healthcare and defense sectors. He has been awarded fellowships and grants from CSIR, DRDO, ICMR, INSA, and others.
Professor Mallika Pathak is a leading academic at Miranda House, University of Delhi. Her research focuses on molecular modeling, drug-molecule interactions, and water remediation. She has published extensively, contributed to international collaborations, and holds multiple patents.
Professor Pathak has received numerous honors, including the Australian Leadership Award Fellowship (2013), ‘Most Promising Innovation’ (2016), and the ‘Teaching Excellence Award for Innovation’ (2015) from the University of Delhi. A passionate mentor and curriculum developer, she plays a pivotal role in shaping interdisciplinary research and science education.
Contents
1. Target Oriented Drug Delivery Systems: (Page 3-44)
Preeti Droliya, P. Lishinai Paoteimai, Mallika Pathak
2. Molecular Basis of Targeted Drug Delivery System: (Page 45-78)
Malti Sharma, Shivani and Mallika Pathak
3. Drug Release and Uptake Phenomenon: (Page 79-118)
Kavita Anuragi, Aritra Saha, Pooja Yadav, Ashrit Nair,
Dr. Dharampal Pathak, Dr. Raman Chawla, Dr. Mallika Pathak, and Dr. Navneet Sharma
4. Drug Encapsulation Techniques and Materials: (Page 119-152)
Jyoti Singh, Prerna Bansal
5. Nanomaterials: (Page 153-168)
Subodh Kumar, Vedprakash Meena, Harshita Gupta, Gunjan Sharma, Anika Wahal, Tanu, Sweta Singh, Yogesh Kumar Verma
6. Drug Delivery Factors: (Page 169-196)
Raveena Kumari, Sharda Mahilkar-Sonkar, Sujata Sengupta, Anand Sonkar
7. Factors Affecting Drug Loading and Release: (Page 197-234)
Aritra Saha, Pooja Yadav, Ashrit Nair, Kavita Anuragi,
Dr. Navneet Sharma, Dr. Mallika Pathak
8. Techniques to Measure the Degree of Loading and Release Efficiency, Metabolism and Excretion of Drug Delivery Carriers: (Page 235-260)
Isha Gupta, Sonia Gandhi, Sameer Sapra
9. LIPOSOMES: (Page 261-276)
Reeta, Aagustya Gupta
10. Monomers: (Page 277-290)
Princy, Ashrit Nair, Pooja Yadav, Navneet Sharma
11. Resealed Erythrocyte as Drug Delivery System: (Page 291-306)
Parul Mittal, Pranibha Maheshwari
12. Nanoparticulate System: (Page 307-356)
Parul Mittal, Areeba Khan, Naveen Kumar Mehto, Waseem Ali
13. Solid Lipid Nanoparticles: (Page 357-368)
Areeba Khan, Parul Mittal, Waseem Ali
14. Dendrimers: (Page 369-386)
Reeta, Aagustya Gupta
15. Organogels: (Page 387-402)
Reeta, Himanshi Yadav
16. Multiple Emulsions: (Page 403-418)
Reeta and Aagustya Gupta
17. Nano Emulsions: (Page 419-438)
Reeta and Himanshi Yadav
18. Overview and Application of Aquasomes, Pharmacosomes, Liquid Crystalline Systems, Protein and Peptide Based Drug Delivery Systems: (Page 439-484)
Ashrit Nair, Lalita Verma, Apoorv, Abdul Qadir, Pooja Yadav, Kavita Anuragi, Bhupendra Singh Butola
19. Polymers in Drug Encapsulation and Drug Delivery: (Page 485-514)
Subodh Kumar, Venkatesh Anand Iyer, Somya Chaaudhary, Yogesh Kumar Verma
20. Polymers in Drug Encapsulation and Drug Delivery: (Page 515-532)
Ved Prakash Meena, Priyanka Surya, Sarika Tomar,
Rakesh Kumar Sharma, Venkatesh Anand Iyer, Emansi Yadav, Harshita Gupta1, Sweta Singh
21. Drug Discovery, Lead Identification and Lead Optimization, Chemical, Pharmaceutical and Clinical Technology Development: (Page 535-558)
Varnika Khattar, Simran Chopra, Navneet Sharma
22. Investigational New Drug and It’s Applications: (Page 559-574)
Ayush Kumar, Priyam Mangal, Mangesh Pradeep Kulkarni, Chandan Bhogendra Jha, Rashi Mathur, Rajesh Kumar
23. Clinical Trials and Its Phases: (Page 575-588)
Dr. Anoushka Khanna and Ms. Shrutika Sharma
24. A Brief Overview and Recent Advances in Pilot Plant Scale-Up Techniques: (Page 589-618)
Chandan Bhogendra Jha, Priyam Mangal, Ayush Kumar, Chitrangda Singh, Kuntal Manna, Rajesh Kumar, Rashi Mathur
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